Kurtikyan, Tigran Stepan
Head of the Laboratory of Optical Spectroscopy,
Molecule Structure Research Center NAS RA,
26 Azatutyan Ave., 375014, Yerevan, Armenia
Head of the Laboratory of Instrumental Methods of Analysis,
Armenian Research Institute of Applied Chemistry,
5/2 Artashat Str., 375053, Yerevan, Armenia
e-mail: tkurt@msrc.am
fax : (37410) 282267
phone : (37410) 563249(home),(37410) 287423 (office)
Dr. Kurtikyan has created biomimetic microporous systems containing coordinatively unsaturated metal atoms. Author of more than 120 publications.

1993 Individual grant of the International Science Foundation.
1998-2001 ISTC Award # A-21 ( US collaborator Prof. C.E Strouse, UCLA, USA ) // Spectral study of the mechanism of catalytic CO-oxidation by low-temperature Co-porphyrin layers.
2001-2004 INTAS Award # 911( Coordinator - Prof. J. S. Ogden, UK ) // Reactions of metal atoms, clusters and complexes in matrices.
2003-2004 NFSAT/CRDF- Award .# CH-053-02/BGP-12001( US Collaborator - Prof. J. A. Goodwin, Coastal Carolina University, SC, USA) // Spectral study of the O-atom transfer reactions performed by nitro-complexes of metalloporphyrins.
2003-2005 CRDF Award #AC2-2520-TB-03 ( US Collaborator Prof. P. C. Ford, University of California, Santa Barbara, USA) // Spectral and kinetic study of NOx reactions with Metalloporphyrins.
2004-2007 ISTC Award # A-484 ( US Collaborators: Prof. C. E. Strouse, Prof. J. A. Goodwin and Prof. P. C. Ford ) //Gas sensing, catalytic and heme-modeling properties of metalloporphyrins sublimed layers.
2005 Prize of the President of the Republic of Armenia for Scientific Researches in the Field of Natural Sciences.

Dr. Kurtikyan's research seeks to understand the role of metal porphyrins and related metal complexes in the possible catalytic activities and sensor properties of such systems in their interactions with small molecules such as nitric oxide, dioxygen, carbon monoxide and nitrogen dioxide. These chemical systems are valuable models of proteins and enzymes that have crucial roles in the control of blood pressure, neurological signaling and immune response in humans and therefore have drown considerable attention from the biomedical community. Dr. Tigran Kurtikyan's laboratories are equipped with modern spectroscopic apparatus including FT-IR and FT Raman spectrometers, dispersive Raman spectrometers, numerous UV-vis spectrophotometers, Helium closed cycle refrigeration systems for matrix isolation studies, etc. The main direction of investigation is low-temperature stabilization and spectral characterization of the intermediates formed in the course of interactions of various ligands with metaloporphyrins of biological relevance to throw light on the mechanism of transformations taking place in biological systems. Methods are developed to investigate these interactions spectroscopically without hindering the effects that occur in solvents. A number of intermediates were stabilized at low-temperature conditions and spectrally characterized as well as the number of reactions performed by porphyrins metallocenters were found. Especially productive were the investigations devoted to nitrogen oxide interactions with heme-modeling metalloporphyrins. An elusive 5-coordinate nitrito intermediate of iron-porphyrins has been recently characterized that transfers to nitrosyl-iron porphyrin when completed. This observation throws light on the recently discovered therapeutic property of nitrites as vasodilation agents. Based on the metallocomplexes of meso-monopyridyl-tri-phenylporhyrins Dr. Kurtikyan has created biomimetic microporous systems containing coordinatively unsaturated metal atoms of biological importance (Fe, Co, Mn). These are the first such systems anywhere and his work has shown that they can have great practical use such as selective adsorbents, oxidation catalysts, and sensors.

List of Publications